[In progress] Princeton Brain Development Project + Meta-analysis
Updated: Aug 3, 2020
"The Princeton Brain Development project aims to model the number of brain connections during our life. Connections between brain cells are called synapses. Babies produce thousands of synapses per second. This leads to a peak in synapse density early in childhood. After this peak, the unused synapses are slowly eliminated again, which leads to a slow decline in synapse density that reaches a stable plateau during adulthood. Understanding the shape of this curve is important to understand diseases like autism and schizophrenia. The Princeton Brain Development project collects data from original research papers. We do not limit ourselves to data obtained from human brains, since most pre-clinical work is done in non-human species."
Henk-Jan Boele, M.D., Ph.D., Princeton Neuroscience Institute
Samuel Wang, Professor of Molecular Biology and Princeton Neuroscience Institute